All kick-off times are local
For 2007/8 results, click here
| Date | Fixture | Time | Venue | Report | |
| September | |||||
| 5 | Connacht v Ospreys | 18.30 | Sportsground | 3-16 | |
| 5 | Dragons v Glasgow | 19.05 | Rodney Parade | 6-12 | |
| 5 | Edinburgh v Munster | 19.30 | Murrayfield | 15-20 | |
| 5 | Ulster v Scarlets | 19.30 | Ravenhill | 9-16 | |
| 6 | Cardiff Blues v Leinster | 19.30 | Arms Park | 16-16 | |
| 9 | Ospreys v Cardiff Blues | 19.35 | Liberty Stadium | 32-10 | |
| 10 | Dragons v Scarlets | 19.05 | Rodney Parade | 25-27 | |
| 12 | Cardiff Blues v Ulster | 19.05 | Cardiff Arms Park | 16-15 | |
| 12 | Glasgow v Ospreys | 19.30 | Firhill | 18-21 | |
| 12 | Leinster v Edinburgh | 19.30 | RDS | 52-6 | |
| 13 | Scarlets v Connacht | 17.30 | Stradey Park | 45-3 | |
| 14 | Munster v Dragons | 18.00 | Musgrave Park | 50-6 | |
| 19 | Connacht v Glasgow | 18.30 | Sportsground | 15-8 | |
| 19 | Edinburgh v Scarlets | 19.30 | Murrayfield | 32-12 | |
| 19 | Leinster v Ospreys | 19.35 | RDS | 19-13 | |
| 19 | Ulster v Dragons | 19.35 | Ravenhill | 14-16 | |
| 20 | Munster v Cardiff Blues | 19.30 | Musgrave Park | 28-20 | |
| 26 | Cardiff Blues v Connacht | 19.05 | Cardiff Arms Park | 58-0 | |
| 26 | Dragons v Edinburgh | 19. 30 | Rodney Parade | 11-9 | |
| 26 | Glasgow v Scarlets | 19.30 | Firhill | 34-20 | |
| 27 | Ospreys v Ulster | 17.30 | Liberty Stadium | 43-0 | |
| 28 | Leinster v Munster | 19.00 | RDS | 0-18 | |
| October | |||||
| 3 | Ulster v Edinburgh | 19.30 | Ravenhill | 13-9 | |
| 4 | Munster v Glasgow | 19.00 | Thomond Park | 25-17 | |
| 5 | Connacht v Leinster | 18.00 | Sportsground | 19-18 | |
| 24 | Connacht v Edinburgh | 18.30 | Sportsground | - | |
| 24 | Glasgow v Leinster | 19.30 | Firhill | - | |
| 25 | Ulster v Munster | 19.30 | Ravenhill | - | |
| November | |||||
| 28 | Scarlets v Munster | 19.05 | Parc y Scarlets | - | |
| 28 | Edinburgh v Ospreys | 19.30 | Murrayfield | - | |
| 28 | Glasgow v Cardiff Blues | 19.30 | Firhill | - | |
| 28 | Ulster v Connacht | 19.30 | Ravenhill | - | |
| 29 | Leinster v Dragons | 17.30 | RDS | - | |
| December | |||||
| 19 | Dragons v Ospreys | 19.05 | Rodney Parade | - | |
| 20 | Scarlets v Cardiff Blues | 17.30 | Parc y Scarlets | - | |
| 26 | Dragons v Cardiff Blues | 14.05 | Rodney Parade | - | |
| 26 | Edinburgh v Glasgow | 19.30 | Murrayfield | - | |
| 27 | Ospreys v Scarlets | 17.30 | Liberty Stadium | - | |
| 27 | Ulster v Leinster | 19.30 | Ravenhill | - | |
| 28 | Connacht v Munster | 18.00 | Sportsground | - | |
| 31 | Cardiff Blues v Ospreys | 14.05 | Arms Park | - | |
| January | |||||
| 1 | Scarlets v Dragons | 17.15 | Parc y Scarlets | - | |
| 2 | Glasgow v Edinburgh | 19.30 | Firhill | - | |
| 2 | Leinster v Connacht | 19.30 | RDS | - | |
| 3 | Munster v Ulster | 17.30 | tbc | - | |
| 9 | Connacht v Scarlets | tbc | Sportsground | - | |
| 9 | Edinburgh v Ulster | tbc | Murrayfield | - | |
| 9 | Glasgow v Dragons | tbc | Firhill | - | |
| 9 | Leinster v Cardiff Blues | tbc | RDS | - | |
| 9 | Ospreys v Munster | tbc | Liberty Stadium | - | |
| February | |||||
| 20 | Cardiff Blues v Glasgow | tbc | Arms Park | - | |
| 20 | Dragons v Ulster | tbc | Rodney Parade | - | |
| 20 | Scarlets v Leinster | tbc | Parc y Scarlets | - | |
| 20 | Munster v Edinburgh | tbc | tbc | - | |
| 20 | Ospreys v Connacht | tbc | Liberty Stadium | - | |
| March | |||||
| 6 | Connacht v Cardiff Blues | tbc | Sportsground | - | |
| 6 | Dragons v Munster | tbc | Rodney Parade | - | |
| 6 | Scarlets v Edinburgh | tbc | Parc y Scarlets | - | |
| 6 | Ospreys v Leinster | tbc | Liberty Stadium | - | |
| 6 | Ulster v Glasgow | tbc | Ravenhill | - | |
| 27 | Cardiff Blues v Scarlets | tbc | Arms Park | - | |
| 27 | Edniburgh v Connacht | tbc | Murrayfield | - | |
| 27 | Glasgow v Munster | tbc | Firhill | - | |
| 27 | Leinster v Ulster | tbc | RDS | - | |
| 27 | Ospreys v Dragons | tbc | Liberty Stadium | - | |
| April | |||||
| 3 | Connacht v Dragons | tbc | Sportsground | - | |
| 3 | Edinburgh v Cardiff Blues | tbc | Murrayfield | - | |
| 3 | Scarlets v Glasgow | tbc | Parc y Scarlets | - | |
| 3 | Munster v Leinster | tbc | tbc | - | |
| 3 | Ulster v Ospreys | tbc | Ravenhill | - | |
| 17 | Cardiff Blues v Dragons | tbc | Arms Park | - | |
| 17 | Edinburgh v Leinster | tbc | Murrayfield | - | |
| 17 | Glasgow v Ulster | tbc | Firhill | - | |
| 17 | Scarlets v Ospreys | tbc | Parc y Scarlets | - | |
| 17 | Munster v Connacht | tbc | tbc | - | |
| 24 | Dragons v Connacht | tbc | Rodney Parade | - | |
| 24 | Leinster v Glasgow | tbc | RDS | - | |
| 24 | Munster v Scarlets | tbc | tbc | - | |
| 24 | Ospreys v Edinburgh | tbc | Liberty Stadium | - | |
| 24 | Ulster v Cardiff Blues | tbc | Ravenhill | - | |
| May | |||||
| 8 | Cardiff Blues v Munster | tbc | Arms Park | - | |
| 8 | Connacht v Ulster | tbc | Sportsground | - | |
| 8 | Edinburgh v Dragons | tbc | Murrayfield | - | |
| 8 | Leinster v Scarlets | tbc | RDS | - | |
| 8 | Ospreys v Glasgow | tbc | Liberty Stadium | - | |
| 15 | Cardiff Blues v Edinburgh | tbc | Arms Park | - | |
| 15 | Dragons v Leinster | tbc | Rodney Parade | - | |
| 15 | Glasgow v Connacht | tbc | Firhill | - | |
| 15 | Scarlets v Ulster | tbc | Parc y Scarlets | - | |
| 15 | Munster v Ospreys | tbc | tbc | - | |