The Super 14's top qualfiers, the Crusaders, will host the Hurricanes in next weekend's first semi-final and the Waratahs - who finished the regular season second after a 18-11 win over the Reds - will host the Sharks in the other semi-final.
The Sharks will travel to Sydney to take on the Waratahs in the Super 14 semi-finals after doing the business against the Chiefs 47-25 in an entertaining match in the last round-robin match of the tournament in Durban on Saturday.
The Bulls handed the Cheetahs a 40 point drubbing in Bloemfontein on Saturday, running in eight tries to win 60-20 in their last Super 14 game of the 2008 season.
The Stormers failed once again to collect maximum points in their 22-13 win over the brave Lions in a scrappy Super 14 derby match at Ellis Park on Saturday.
A Super 14 season which started so well and finished so brilliantly for the Western Force has been labelled a wasted opportunity by coach John Mitchell.
The Sharks and Stormers can thank the Blues for their effort in beating the Hurricanes to make their passage into the semi-finals that much simpler.
Then there were two away spots remaining as the Waratahs beat the Reds 18-11 to seal a Super 14 home semi-final at the Suncorp Stadium on Saturday.
It may have been a dead rubber, but tell that to the Highlanders. The men from Otago never gave champions-to-be the Crusaders a sniff of a chance at AMI Stadium on Saturday, winning the final Super 14 game 26-14.
It has been a rotten season for the Highlanders, but amidst the gloom there have been some bright spots for full-back Paul Williams.
Stormers captain Jean de Villiers realises beating the Lions on Saturday would not be easy, but says his team are confident in their ability to pull it off.
The Western Force came from 22-0 behind to beat the Brumbies 29-22 in a hard-fought Super 14 derby encounter at Subiaco Oval in Perth on Friday.
It will be a case of "all or nothing" for the Waratahs, Stormers, Sharks and the Chiefs as they each make a final bid to qualify for the Super 14 semi-finals in the final weekend of round-robin action on Saturday.
Blues coach David Nucifora has made a case for extended play-offs system in the Super 14 after his side's exciting 19-17 win over the Hurricanes on Friday.
The Blues held on for a dramatic 19-17 victory over the Hurricanes at Eden Park on Friday, and in doing so maintained their slender Super 14 semi-final hopes.
Bulls and Springbok flanker Wikus van Heerden has signed with Saracens and will join the English club in November.